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PHARMACEUTICAL PURIFIED WATER SYSTEMS, USP PURIFIED WATER SYSTEMS, REVERSE OSMOSIS EDI SYSTEMS, HIGH PURITY WATER SYSTEM, DEIONIZED WATER SYSTEMS |
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UNIQUE FEATURES n Exceptional Quality USP Purified Water: Typical output water measures 0.3-1.2 mS/cm electrical conductivity, 70-150 ppb TOC, 1-10 cfu/ml bacteria content. Consistently meets USP 23-29 Purified Water standards n Exceptionally Consistent Purified Water Quality: Replacement of conventional de-ionizing resin beds with electrodeionizing modules (EDI) results in highy consistent purified water quality and lower ion content n Exceptional Economy: Costs fraction of conventional, DI resin based USP purified water systems to purchase, to operate and to maintain n Exceptionally Space-Saving Design: Small 76 cm x 146 cm footprint for 1,600 L/hr capacity unit n Sanitary Construction: Fully enclosed2 inside stainless-steel cabinet. High-purity, low-extractable PVC output piping better than PVDF or stainless-steel. Cold-sterilizable with internal cleaning and sanitizing system n Ultimate Contamination Control: Totally Sealed System prevents infusion of environmental contaminants. n Integrated Re-circulation Loop: Closed-Loop purified water distribution system (see below). Unused Purified Water from production area is continuously recycled to water purification section where it gets repeatedly purified with every pass. Continuously purges out bacteria generated in pipelines instead of accumulating them, as in conventional pharmaceutical process water delivery systems. n Exceptionally Simplified Distribution System Design: Only a few passive piping components required for completing delivery system. No storage tanks, no breathing filters, no re-circulation pumps, no UV lights, no sub-micron filters, no heat exchangers, no clean steam generators required. n Water-Saving Design: 60-70% overall water recovery. n Energy-Saving Design: High-efficiency EDI power supply. Cold re-circulation loop. Only 2.4 watt.hours of total energy consumption per liter of purified water, including delivery system. n Environmentally Friendly Design: No chemicals used to regenerate de-ionizing resins. No chemical discharge to sewer other than impurities present in source water n Easy Installation: Integrated RO/EDI design for Plug-n-Go installation. Only pre-treatment components and simple, Purified Water delivery loop passive piping required to complete installation n Easy Validation: Factory-assembled, factory pre-qualified water purification unit simplifies on-site qualification and validation of the pharmaceutical Purified Water process water system. Factory OQ and PQ certification provided with each system n Easy Operation: Single-switch daily operation with manual over-ride. Quick stabilization avoids 24/7 operation. Ergonomic instrumentation and control panel n Easy Sanitizing: Single-shot cold sanitizing of water purification unit and the distribution piping with built-in cleaning and sanitizing system. No steam generator required n Easy Maintenance: Only single moving part (RO pump) in the entire water system including delivery piping. Single circuit board electronics for all instrumentation. Integrated EDI power supply. Very few things to break down |
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With over 27 years of experience in pharmaceutical water systems, when you go with Blue Spring, you are in safe hands !
For sales and applications assistance, please click here To learn more about EDI and about USP standards, please click here
1 According to U.S. FDA, USP purified water and USP WFI are components or “ingredient materials” as they are termed by the USP, intended to be used in the production of drug products. Neither FDA nor USP considers them as drug products. These two water categories are popularly used within pharmaceutical and medical device manufacturing establishments. 2 Except WFI-700R-EDI and WFI-1400R-EDI models in which RO modules are outside cabinet |
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PRODUCE HIGH QUALITY PHARMACEUTICAL USP PURIFIED WATER1 PER USP 23-29 For USP Water for Injection systems, click here |

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Specify "R" option for closed-loop output. Click here to learn more about Closed Loop Output Systems |
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TYPICAL CLOSED-LOOP OUTPUT CONFIGURATION OF BLUE SPRING SYSTEM WP-R-EDI IN PRODUCTION OF PHARMACEUTICAL PRODUCTS |
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WP-R-EDI SERIES |
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Blue Spring Corporation is the pioneer (1982) in commercialization of reverse osmosis technology for the production of pharmaceutical USP water. Now, with the addition of the latest electrodeionization (EDI) technology, and a storage-tank-less re-circulating closed loop output feature, the new breed of BLUE SPRING WP-R-EDI Series pharmaceutical water purification systems produce even higher quality pharmaceutical grade purified water which surpasses the latest USP 29 standards for Purified Water1 for pharmaceutical process water and pharmaceutical production uses. Also suitable for the production of high purity deionized water for high pressure boilers, semi-conductor manufacturing and other industrial uses. For sales and applications assistance, please click here
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LATEST COMBINATION REVERSE OSMOSIS / ELECTRODEIONIZATION SYSTEMS WITH BUILT-IN, PUMP-LESS CLOSED LOOP RECIRCULATION OUTPUT CONFIGURATION MAKES ION-EXCHANGE DEIONIZATION SYSTEMS OBSOLETE |
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SPECIFICATIONS |
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MODEL |
WP-240-EDI |
WP-400-EDI |
WP-800-EDI |
WP-1600-EDI |
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SIZE (WxLxH) |
56 x 118 x 145 cm |
76 x 146 x 146 cm |
91 x 145 x 152 cm |
91 x 183 x 152 cm |
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SHIP. WT. |
272 kg |
335 kg |
580 kg |
940 kg |
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ELECTRICAL |
230 VAC/1 ph/14A |
460 VAC/3 ph/3.7A |
460 VAC/3ph/7.3A |
460 VAC/3ph/14A |
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OUTPUT PORT |
1" CIP Clamp |
1" CIP Clamp |
1.25" CIP Clamp |
1.5" CIP Clamp |
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OUTPUT FLOW |
770-935 lph @ 25oC |
1,400-1,700 lph @ 25oC |
2,800-3,400 lph @ 25oC |
5,400-6,600 lph @ 25oC |
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SUPPLY WATER |
21-25 lpm |
30-45 lpm |
65-85 lpm |
130-170 lpm |
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SUPPLY WATER |
EPA quality municipal water. 20-60 psig pressure. 18-32 oC temperature. Pre-softening of feed water required, to reduce hardness below 5 mg/L. May require carbon filtration, if chlorine or other disinfectant is present in feed water. Contact us for details. |
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OUTPUT WATER |
Output water meets Purified Water specifications per USP 29. Typical electrical conductivity 0.3 - 1.2 mS/cm, Typical TOC 70-150 ppb, Typical bacteria count 1-10 cfu/ml (without additional filtration or UV sterilization). Note: day-to-day output water quality will depend on sanitizing schedule and general equipment maintenance. |
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